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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1222489
Molecular formula	C29H31F3N2O3
IUPAC name	7-methoxy-1-(2-methoxyethyl)-5-[(2-methoxyphenyl)methyl]-2-(4-propan-2-ylphenyl)-4-(trifluoromethyl)benzimidazole
Molecular weight	512.573
Hydrogen bond acceptor	7
Hydrogen bond donor	0
XlogP	6.8
Synonyms	SCHEMBL2496420 2-(4-isopropylphenyl)-7-methoxy-5-(2-methoxybenzyl)-1-(2-methoxyethyl)-4-(trifluoromethyl)-1H-benzo[d]imidazole BDBM50325516
Inchi Key	CUUQJCBKILQBIV-UHFFFAOYSA-N
Inchi ID	InChI=1S/C29H31F3N2O3/c1-18(2)19-10-12-20(13-11-19)28-33-26-25(29(30,31)32)22(16-21-8-6-7-9-23(21)36-4)17-24(37-5)27(26)34(28)14-15-35-3/h6-13,17-18H,14-16H2,1-5H3
PubChem CID	49864798
ChEMBL	CHEMBL1222489
IUPHAR	N/A
BindingDB	50325516
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
51140	Extracellular calcium-sensing receptor	P41180	CASR	Homo sapiens (Human)	1078

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