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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	ADX-71743
Molecular formula	C17H19NO2
IUPAC name	6-(2,4-dimethylphenyl)-2-ethyl-6,7-dihydro-5H-1,3-benzoxazol-4-one
Molecular weight	269.344
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	3.8
Synonyms	(+)-6-(2,4-dimethylphenyl)-2-ethyl-6,7-dihydrobenzo[d]oxazol-4(5h)-one ADX71743, >=98% (HPLC) 6-(2,4-Dimethylphenyl)-2-ethyl-6,7-dihydro-4(5H)-benzoxazolone GTPL6217 (+/-)-ADX 71743 AKOS030210948 J3.526.068D ADX71743 6-(2,4-dimethylphenyl)-2-ethyl-4,5,6,7-tetrahydro-1,3-benzoxazol-4-one D0K2XD ADX 71743 [ Show all ]
Inchi Key	CPKZCQHJDFSOJT-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H19NO2/c1-4-16-18-17-14(19)8-12(9-15(17)20-16)13-6-5-10(2)7-11(13)3/h5-7,12H,4,8-9H2,1-3H3
PubChem CID	53391766
ChEMBL	N/A
IUPHAR	6217
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
553468	Metabotropic glutamate receptor 7	Q14831	GRM7	Homo sapiens (Human)	915
553469	Metabotropic glutamate receptor 7	P35400	Grm7	Rattus norvegicus (Rat)	915

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