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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3356410
Molecular formula	C24H26F3N3O5
IUPAC name	2-[(5R)-4-[2-[3-(2-methylpropoxycarbonyl)phenyl]acetyl]-8-(trifluoromethyl)-1,2,3,5-tetrahydropyrido[2,3-e][1,4]diazepin-5-yl]acetic acid
Molecular weight	493.483
Hydrogen bond acceptor	10
Hydrogen bond donor	2
XlogP	3.5
Synonyms	BDBM50041423
Inchi Key	COYVCOHEUZGEOW-GOSISDBHSA-N
Inchi ID	InChI=1S/C24H26F3N3O5/c1-14(2)13-35-23(34)16-5-3-4-15(10-16)11-20(31)30-9-8-28-22-17(18(30)12-21(32)33)6-7-19(29-22)24(25,26)27/h3-7,10,14,18H,8-9,11-13H2,1-2H3,(H,28,29)(H,32,33)/t18-/m1/s1
PubChem CID	118721528
ChEMBL	CHEMBL3356410
IUPHAR	N/A
BindingDB	50041423
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
443548	Bombesin receptor subtype-3	O54798	Brs3	Mus musculus (Mouse)	399
443549	Bombesin receptor subtype-3	P32247	BRS3	Homo sapiens (Human)	399

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