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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL170493
Molecular formula	C32H31BrN6O4S
IUPAC name	N-[6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(4-methylphenyl)-2-pyridin-2-ylpyrimidin-4-yl]-4-tert-butylbenzenesulfonamide
Molecular weight	675.602
Hydrogen bond acceptor	10
Hydrogen bond donor	1
XlogP	6.6
Synonyms	BDBM50107556 N-[2-(2-Pyridinyl)-5-(4-methylphenyl)-6-[2-(5-bromo-2-pyrimidinyloxy)ethoxy]-4-pyrimidinyl]-4-(tert-butyl)benzenesulfonamide N-{6-[2-(5-Bromo-pyrimidin-2-yloxy)-ethoxy]-2-pyridin-2-yl-5-p-tolyl-pyrimidin-4-yl}-4-tert-butyl-benzenesulfonamide
Inchi Key	CILITEGULAWVQL-UHFFFAOYSA-N
Inchi ID	InChI=1S/C32H31BrN6O4S/c1-21-8-10-22(11-9-21)27-29(39-44(40,41)25-14-12-23(13-15-25)32(2,3)4)37-28(26-7-5-6-16-34-26)38-30(27)42-17-18-43-31-35-19-24(33)20-36-31/h5-16,19-20H,17-18H2,1-4H3,(H,37,38,39)
PubChem CID	44381125
ChEMBL	CHEMBL170493
IUPHAR	N/A
BindingDB	50107556
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
42777	Endothelin-1 receptor	Q29010	EDNRA	Sus scrofa (Pig)	427

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