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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL455718
Molecular formula	C25H23F2N3O2
IUPAC name	1-(2,6-difluorophenyl)-3-[[4-(2,3,4,5-tetrahydro-1-benzazepine-1-carbonyl)phenyl]methyl]urea
Molecular weight	435.475
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	4.4
Synonyms	BDBM50246890 SCHEMBL5238932 1-(4-[3-(2,6-Difluorophenyl)ureidomethyl]benzoyl)-2,3,4,5-tetrahydro-1H-1-benzazepine
Inchi Key	CHVDHGULKQMPAV-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H23F2N3O2/c26-20-8-5-9-21(27)23(20)29-25(32)28-16-17-11-13-19(14-12-17)24(31)30-15-4-3-7-18-6-1-2-10-22(18)30/h1-2,5-6,8-14H,3-4,7,15-16H2,(H2,28,29,32)
PubChem CID	9954641
ChEMBL	CHEMBL455718
IUPHAR	N/A
BindingDB	50246890
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
42318	Oxytocin receptor	P30559	OXTR	Homo sapiens (Human)	389
42319	Vasopressin V2 receptor	P30518	AVPR2	Homo sapiens (Human)	371

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