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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1085616
Molecular formula	C25H24F2N4O4
IUPAC name	5-(3,5-difluorophenyl)-2-[[3-[1-(5-hydroxypyridin-2-yl)pyrazol-3-yl]-2-methylpropanoyl]amino]cyclohexene-1-carboxylic acid
Molecular weight	482.488
Hydrogen bond acceptor	8
Hydrogen bond donor	3
XlogP	3.8
Synonyms	BDBM50319241 5-(3,5-difluorophenyl)-2-(3-(1-(5-hydroxypyridin-2-yl)-1H-pyrazol-3-yl)-2-methylpropanamido)cyclohex-1-enecarboxylicacid
Inchi Key	CGDIEFVZLOERLL-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H24F2N4O4/c1-14(8-19-6-7-31(30-19)23-5-3-20(32)13-28-23)24(33)29-22-4-2-15(11-21(22)25(34)35)16-9-17(26)12-18(27)10-16/h3,5-7,9-10,12-15,32H,2,4,8,11H2,1H3,(H,29,33)(H,34,35)
PubChem CID	46890301
ChEMBL	CHEMBL1085616
IUPHAR	N/A
BindingDB	50319241
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
41210	Hydroxycarboxylic acid receptor 2	Q8TDS4	HCAR2	Homo sapiens (Human)	363

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