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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL361051
Molecular formula	C15H14F3NO5
IUPAC name	(1R,2R,3R,5R,6R)-2-amino-3-[(2,6-difluorophenyl)methoxy]-6-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic acid
Molecular weight	345.274
Hydrogen bond acceptor	9
Hydrogen bond donor	3
XlogP	-1.7
Synonyms	BDBM50151491 (1R,2R,3R,5R,6R)-2-Amino-3-(2,6-difluoro-benzyloxy)-6-fluoro-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid
Inchi Key	CCAMCPGAZOOUOO-JAGWWQSPSA-N
Inchi ID	InChI=1S/C15H14F3NO5/c16-8-2-1-3-9(17)6(8)5-24-10-4-7-11(14(7,18)12(20)21)15(10,19)13(22)23/h1-3,7,10-11H,4-5,19H2,(H,20,21)(H,22,23)/t7-,10-,11+,14-,15+/m1/s1
PubChem CID	11484739
ChEMBL	CHEMBL361051
IUPHAR	N/A
BindingDB	50151491
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
38397	Metabotropic glutamate receptor 2	P31421	Grm2	Rattus norvegicus (Rat)	872
558446	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872

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