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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2179912
Molecular formula	C23H21ClF3N3O2S
IUPAC name	6-(4-tert-butylphenyl)sulfonyl-7-chloro-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepine
Molecular weight	495.945
Hydrogen bond acceptor	8
Hydrogen bond donor	1
XlogP	6.2
Synonyms	CBQIYLKRMLUSFL-UHFFFAOYSA-N SCHEMBL1085952 6-[(4-tert-butylphenyl)sulfonyl]-7-chloro-2-(trifluoromethyl)-6,11-dihydro-5H-pyrido[2,3-b][1,5]benzodiazepine BDBM50400253
Inchi Key	CBQIYLKRMLUSFL-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H21ClF3N3O2S/c1-22(2,3)15-8-10-16(11-9-15)33(31,32)30-13-14-7-12-19(23(25,26)27)29-21(14)28-18-6-4-5-17(24)20(18)30/h4-12H,13H2,1-3H3,(H,28,29)
PubChem CID	66901760
ChEMBL	CHEMBL2179912
IUPHAR	N/A
BindingDB	50400253
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
38130	Bombesin receptor subtype-3	O54798	Brs3	Mus musculus (Mouse)	399
38131	Bombesin receptor subtype-3	P32247	BRS3	Homo sapiens (Human)	399

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