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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL198562
Molecular formula	C30H30Cl2N4O3
IUPAC name	N-[2-[4-(3-cyanophenyl)phenyl]ethyl]-N-[2-(3,5-dichloroanilino)-2-oxoethyl]-3-[(3S)-3-hydroxypyrrolidin-1-yl]propanamide
Molecular weight	565.495
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	4.7
Synonyms	BDBM50174832 N-[2-(3''-cyano-biphenyl-4-yl)-ethyl]-N-[(3,5-dichloro-phenylcarbamoyl)-methyl]-3-((S)-3-hydroxy-pyrrolidin-1-yl)-propionamide
Inchi Key	BUGRTZMNHWAJRY-NDEPHWFRSA-N
Inchi ID	InChI=1S/C30H30Cl2N4O3/c31-25-15-26(32)17-27(16-25)34-29(38)20-36(30(39)10-12-35-11-9-28(37)19-35)13-8-21-4-6-23(7-5-21)24-3-1-2-22(14-24)18-33/h1-7,14-17,28,37H,8-13,19-20H2,(H,34,38)/t28-/m0/s1
PubChem CID	10281308
ChEMBL	CHEMBL198562
IUPHAR	N/A
BindingDB	50174832
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
33015	Melanin-concentrating hormone receptor 1	Q99705	MCHR1	Homo sapiens (Human)	422
33014	Melanin-concentrating hormone receptor 2	Q969V1	MCHR2	Homo sapiens (Human)	340

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