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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3899595
Molecular formula	C33H42N6O
IUPAC name	2-(3,5-dimethyl-2H-indazol-4-yl)-4-[(3S,4S)-4-methoxy-3-methylpiperidin-1-yl]-6-(2-methyl-5-propan-2-ylphenyl)-7,8-dihydro-5H-pyrido[4,3-d]pyrimidine
Molecular weight	538.74
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	6.7
Synonyms	N/A
Inchi Key	BSVQZQJKSVHJKW-ZTOMLWHTSA-N
Inchi ID	InChI=1S/C33H42N6O/c1-19(2)24-10-8-20(3)28(16-24)38-14-12-26-25(18-38)33(39-15-13-29(40-7)22(5)17-39)35-32(34-26)30-21(4)9-11-27-31(30)23(6)36-37-27/h8-11,16,19,22,29H,12-15,17-18H2,1-7H3,(H,36,37)/t22-,29-/m0/s1
PubChem CID	134134380
ChEMBL	CHEMBL3899595
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
548257	C5a anaphylatoxin chemotactic receptor 1	P21730	C5AR1	Homo sapiens (Human)	350

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