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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1681884
Molecular formula	C27H34Cl2FN5O
IUPAC name	5-chloro-6-[4-[1-[(4-chloro-2-fluorophenyl)methyl]piperidin-4-yl]-3-cyclopropylpiperazin-1-yl]-N-ethylpyridine-3-carboxamide
Molecular weight	534.501
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	5.0
Synonyms	5-chloro-6-(4-(1-(4-chloro-2-fluorobenzyl)piperidin-4-yl)-3-cyclopropylpiperazin-1-yl)-N-ethylnicotinamide BDBM50337253 SCHEMBL13205745
Inchi Key	BNSISGSQGFUVIN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H34Cl2FN5O/c1-2-31-27(36)20-13-23(29)26(32-15-20)34-11-12-35(25(17-34)18-3-4-18)22-7-9-33(10-8-22)16-19-5-6-21(28)14-24(19)30/h5-6,13-15,18,22,25H,2-4,7-12,16-17H2,1H3,(H,31,36)
PubChem CID	53319882
ChEMBL	CHEMBL1681884
IUPHAR	N/A
BindingDB	50337253
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
28405	C-X-C chemokine receptor type 3	P49682	CXCR3	Homo sapiens (Human)	368

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