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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL271319
Molecular formula	C28H22N4O
IUPAC name	4-[3-(2,4-dimethylimidazol-1-yl)phenyl]-8-(2-phenylethynyl)-1,3-dihydro-1,5-benzodiazepin-2-one
Molecular weight	430.511
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	5.0
Synonyms	SCHEMBL5869161 BDBM50372878 4-[3-(2,4-Dimethyl-imidazol-1-yl)-phenyl]-8-phenylethynyl-1,3-dihydro-benzo[b][1,4]diazepin-2-one BNDLOWQLTPXTJB-UHFFFAOYSA-N
Inchi Key	BNDLOWQLTPXTJB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H22N4O/c1-19-18-32(20(2)29-19)24-10-6-9-23(16-24)26-17-28(33)31-27-15-22(13-14-25(27)30-26)12-11-21-7-4-3-5-8-21/h3-10,13-16,18H,17H2,1-2H3,(H,31,33)
PubChem CID	22224972
ChEMBL	CHEMBL271319
IUPHAR	N/A
BindingDB	50372878
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
27992	Metabotropic glutamate receptor 2	P31421	Grm2	Rattus norvegicus (Rat)	872
558112	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872

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