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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL198945
Molecular formula	C29H28Cl2N4O3
IUPAC name	N-[2-[4-(3-cyanophenyl)phenyl]ethyl]-N-[2-(3,5-dichloroanilino)-2-oxoethyl]-2-[(3R)-3-hydroxypyrrolidin-1-yl]acetamide
Molecular weight	551.468
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	4.8
Synonyms	BDBM50174830 N-[2-(3''-cyano-biphenyl-4-yl)-ethyl]-N-[(3,5-dichloro-phenylcarbamoyl)-methyl]-2-((R)-3-hydroxy-pyrrolidin-1-yl)-acetamide
Inchi Key	BFVBGCXATBAVRX-HHHXNRCGSA-N
Inchi ID	InChI=1S/C29H28Cl2N4O3/c30-24-13-25(31)15-26(14-24)33-28(37)18-35(29(38)19-34-10-9-27(36)17-34)11-8-20-4-6-22(7-5-20)23-3-1-2-21(12-23)16-32/h1-7,12-15,27,36H,8-11,17-19H2,(H,33,37)/t27-/m1/s1
PubChem CID	10143980
ChEMBL	CHEMBL198945
IUPHAR	N/A
BindingDB	50174830
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
22664	Melanin-concentrating hormone receptor 1	Q99705	MCHR1	Homo sapiens (Human)	422
22663	Melanin-concentrating hormone receptor 2	Q969V1	MCHR2	Homo sapiens (Human)	340

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