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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL315873
Molecular formula	C31H40N4O5S
IUPAC name	1-[2-[4-[(2-butyl-1,4-dioxo-2,3-diazaspiro[4.4]nonan-3-yl)methyl]phenyl]phenyl]sulfonyl-3-cyclohexylurea
Molecular weight	580.744
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	6.1
Synonyms	N-(Cyclohexylcarbamoyl)-2-[4-(3-butyl-1,4-dioxo-2,3-diazaspiro[4.4]nonane-2-ylmethyl)phenyl]benzenesulfonamide 4''-(3-Butyl-1,4-dioxo-2,3-diaza-spiro[4.4]non-2-ylmethyl)-2-sulfonyl-N-cyclohexylureido biphenyl BDBM50089988
Inchi Key	BEIVIEJLXARNLI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C31H40N4O5S/c1-2-3-21-34-28(36)31(19-9-10-20-31)29(37)35(34)22-23-15-17-24(18-16-23)26-13-7-8-14-27(26)41(39,40)33-30(38)32-25-11-5-4-6-12-25/h7-8,13-18,25H,2-6,9-12,19-22H2,1H3,(H2,32,33,38)
PubChem CID	11801362
ChEMBL	CHEMBL315873
IUPHAR	N/A
BindingDB	50089988
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
21577	Type-1 angiotensin II receptor	P30556	AGTR1	Homo sapiens (Human)	359

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