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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SCHEMBL2773794
Molecular formula	C32H25F3N4O4S
IUPAC name	3-[2-(4-methylphenyl)ethyl]-1-[[4-[2-(5-oxo-4H-1,2,4-oxadiazol-3-yl)phenyl]phenyl]methyl]-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidine-2,4-dione
Molecular weight	618.631
Hydrogen bond acceptor	9
Hydrogen bond donor	1
XlogP	7.2
Synonyms	US8501750, 59 CHEMBL3640124 BDBM99945
Inchi Key	BBWLIANAFFZYLX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C32H25F3N4O4S/c1-19-6-8-20(9-7-19)14-15-38-28(40)26-16-23(17-32(33,34)35)44-29(26)39(31(38)42)18-21-10-12-22(13-11-21)24-4-2-3-5-25(24)27-36-30(41)43-37-27/h2-13,16H,14-15,17-18H2,1H3,(H,36,37,41)
PubChem CID	136052261
ChEMBL	CHEMBL3640124
IUPHAR	N/A
BindingDB	99945
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
19895	Type-1 angiotensin II receptor	P30556	AGTR1	Homo sapiens (Human)	359

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