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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SCHEMBL14671793
Molecular formula	C34H44N6O
IUPAC name	2-(3,5-dimethyl-2H-indazol-4-yl)-4-[(4R)-4-methoxy-3,3-dimethylpiperidin-1-yl]-6-(2-methyl-5-propan-2-ylphenyl)-7,8-dihydro-5H-pyrido[4,3-d]pyrimidine
Molecular weight	552.767
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	7.1
Synonyms	US8846656, 21-AI BDBM134520
Inchi Key	AZVDCMWACRSDFZ-GDLZYMKVSA-N
Inchi ID	InChI=1S/C34H44N6O/c1-20(2)24-11-9-21(3)28(17-24)39-15-13-26-25(18-39)33(40-16-14-29(41-8)34(6,7)19-40)36-32(35-26)30-22(4)10-12-27-31(30)23(5)37-38-27/h9-12,17,20,29H,13-16,18-19H2,1-8H3,(H,37,38)/t29-/m1/s1
PubChem CID	71244720
ChEMBL	N/A
IUPHAR	N/A
BindingDB	134520
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
557828	C5a anaphylatoxin chemotactic receptor 1	P21730	C5AR1	Homo sapiens (Human)	350

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