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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL245671
Molecular formula	C26H30F3N5
IUPAC name	N-(cyclopropylmethyl)-N-[[4-(trifluoromethyl)-7-(2,4,6-trimethylphenyl)-2,5,7,9-tetrazatricyclo[6.4.0.02,6]dodeca-1(8),3,5,9,11-pentaen-3-yl]methyl]propan-1-amine
Molecular weight	469.556
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	6.8
Synonyms	BDBM50203608 cyclopropylmethyl-propyl-[2-trifluoromethyl-8-(2,4,6-trimethyl-phenyl)-8H-1,3a,7,8-tetraaza-cyclopenta[a]inden-3-ylmethyl]-amine SCHEMBL5419888
Inchi Key	AZRZXCRQDGIRRE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H30F3N5/c1-5-11-32(14-19-8-9-19)15-21-23(26(27,28)29)31-25-33(21)20-7-6-10-30-24(20)34(25)22-17(3)12-16(2)13-18(22)4/h6-7,10,12-13,19H,5,8-9,11,14-15H2,1-4H3
PubChem CID	21916343
ChEMBL	CHEMBL245671
IUPHAR	N/A
BindingDB	50203608
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
18447	Corticotropin-releasing factor receptor 1	P34998	CRHR1	Homo sapiens (Human)	444

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