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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MK-3207
Molecular formula	C31H29F2N5O3
IUPAC name	2-[(8R)-8-(3,5-difluorophenyl)-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]-N-[(2R)-2'-oxospiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-5-yl]acetamide
Molecular weight	557.602
Hydrogen bond acceptor	7
Hydrogen bond donor	3
XlogP	2.8
Synonyms	ZINC43203371 2-((R)-8-(3,5-difluorophenyl)-10-oxo-6,9-diazaspiro[4.5]decan-9-yl)-N-((R)-2'-oxo-1,1',2',3-tetrahydrospiro[indene-2,3'-pyrrolo[2,3-b]pyridin]-5-yl)acetamide ABP000446 CS-1449 BCP9000934 DTXSID00241931 PubChem23706 UNII-5C44M1QYCC (8R)-8-(3,5-Difluorophenyl)-10-oxo-n-[(2r)-1,1',2',3-tetrahydro-2'-oxospiro[2h-indene-2,3'-[3h]pyrrolo[2,3-b]pyridin]-5-yl]-6,9-diazaspiro[4.5]decane-9-acetamide hydrochloride 957118-49-9 MK 3207 2-[(8R)-8-(3,5-difluorophenyl)-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]-N-[(2R)-2-oxospiro[1,3-dihydroindene-2,3-1H-pyrrolo[2,3-b]pyridine]-5-yl]acetamide AKOS022184927 D00MXN MK3207 5C44M1QYCC BDBM50356282 FT-0773479 SB19233 W-5629 2-((8R)-8-(3,5-Difluorophenyl)-10-oxo-6,9-diazaspiro(4.5)dec-9-yl)-N-((2R)-2'-oxo-1,1',2',3-tetrahydrospiro(indene-2,3'-pyrrolo(2,3-b)pyridin)-5-yl)acetamide AB0008195 CHEMBL1910936 MK 3207/MK-3207 3858AH BCP02225 DB12424 NCGC00346546-01 6,9-Diazaspiro(4.5)decane-9-acetamide, 8-(3,5-difluorophenyl)-10-oxo-N-((2R)-1,1',2',3-tetrahydro-2'-oxospiro(2H-indene-2,3'-(3H)pyrrolo(2,3-b)pyridin)-5-yl)-, (8R)- C31H29F2N5O3 HY-10301 SCHEMBL992191 [ Show all ]
Inchi Key	AZAANWYREOQRFB-SETSBSEESA-N
Inchi ID	InChI=1S/C31H29F2N5O3/c32-21-10-19(11-22(33)13-21)25-16-35-31(7-1-2-8-31)29(41)38(25)17-26(39)36-23-6-5-18-14-30(15-20(18)12-23)24-4-3-9-34-27(24)37-28(30)40/h3-6,9-13,25,35H,1-2,7-8,14-17H2,(H,36,39)(H,34,37,40)/t25-,30+/m0/s1
PubChem CID	25019940
ChEMBL	CHEMBL1910936
IUPHAR	N/A
BindingDB	50356282
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
17934	Calcitonin gene-related peptide type 1 receptor	Q63118	Calcrl	Rattus norvegicus (Rat)	464
17935	Calcitonin gene-related peptide type 1 receptor	Q16602	CALCRL	Homo sapiens (Human)	461

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