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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SCHEMBL14150876
Molecular formula	C21H19F3N4O3
IUPAC name	1-[3-(difluoromethoxy)phenyl]-N-[2-fluoro-4-[(2S)-morpholin-2-yl]phenyl]pyrazole-4-carboxamide
Molecular weight	432.403
Hydrogen bond acceptor	8
Hydrogen bond donor	2
XlogP	2.8
Synonyms	US9029370, 75 BDBM158281
Inchi Key	AYSYQXMTYDSFRX-LJQANCHMSA-N
Inchi ID	InChI=1S/C21H19F3N4O3/c22-17-8-13(19-11-25-6-7-30-19)4-5-18(17)27-20(29)14-10-26-28(12-14)15-2-1-3-16(9-15)31-21(23)24/h1-5,8-10,12,19,21,25H,6-7,11H2,(H,27,29)/t19-/m1/s1
PubChem CID	71086935
ChEMBL	N/A
IUPHAR	N/A
BindingDB	158281
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
557786	Trace amine-associated receptor 1	Q923Y8	Taar1	Mus musculus (Mouse)	332
557787	Trace amine-associated receptor 1	Q923Y9	Taar1	Rattus norvegicus (Rat)	332

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