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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL394112
Molecular formula	C28H28ClN5
IUPAC name	7-(2-chloro-4,6-dimethylphenyl)-4-methyl-3-[(2-phenylpyrrolidin-1-yl)methyl]-2,5,7,9-tetrazatricyclo[6.4.0.02,6]dodeca-1(8),3,5,9,11-pentaene
Molecular weight	470.017
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	6.9
Synonyms	8-(2-chloro-4,6-dimethyl-phenyl)-2-methyl-3-(2-phenyl-pyrrolidin-1-ylmethyl)-8H-1,3a,7,8-tetraaza-cyclopenta[a]indene BDBM50203622 SCHEMBL14446675
Inchi Key	AYPRBDIXIJJDIB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H28ClN5/c1-18-15-19(2)26(22(29)16-18)34-27-24(11-7-13-30-27)33-25(20(3)31-28(33)34)17-32-14-8-12-23(32)21-9-5-4-6-10-21/h4-7,9-11,13,15-16,23H,8,12,14,17H2,1-3H3
PubChem CID	20780049
ChEMBL	CHEMBL394112
IUPHAR	N/A
BindingDB	50203622
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
17669	Corticotropin-releasing factor receptor 1	P34998	CRHR1	Homo sapiens (Human)	444

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