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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL332721
Molecular formula	C20H22Cl2N4
IUPAC name	N-(cyclopropylmethyl)-3-(2,4-dichlorophenyl)-N-ethyl-1,5-dimethylpyrazolo[4,3-b]pyridin-7-amine
Molecular weight	389.324
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	5.1
Synonyms	BDBM50132932 Cyclopropylmethyl-[3-(2,4-dichloro-phenyl)-1,5-dimethyl-1H-pyrazolo[4,3-b]pyridin-7-yl]-ethyl-amine N-(Cyclopropylmethyl)-N-ethyl-1,5-dimethyl-3-(2,4-dichlorophenyl)-1H-pyrazolo[4,3-b]pyridine-7-amine
Inchi Key	AXSAXWWLBPZENZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H22Cl2N4/c1-4-26(11-13-5-6-13)17-9-12(2)23-19-18(24-25(3)20(17)19)15-8-7-14(21)10-16(15)22/h7-10,13H,4-6,11H2,1-3H3
PubChem CID	44341737
ChEMBL	CHEMBL332721
IUPHAR	N/A
BindingDB	50132932
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
17028	Corticotropin-releasing factor receptor 1	P34998	CRHR1	Homo sapiens (Human)	444

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