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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL17656
Molecular formula	C21H28N4O3S
IUPAC name	7-[bis(2-methoxyethyl)amino]-5-methyl-3-(2,4,6-trimethylphenyl)-[1,3]thiazolo[4,5-d]pyrimidin-2-one
Molecular weight	416.54
Hydrogen bond acceptor	7
Hydrogen bond donor	0
XlogP	3.7
Synonyms	3-Mesityl-5-methyl-7-[bis(2-methoxyethyl)amino]-2,3-dihydrothiazolo[4,5-d]pyrimidine-2-one BDBM50076902 7-[Bis-(2-methoxy-ethyl)-amino]-5-methyl-3-(2,4,6-trimethyl-phenyl)-3H-thiazolo[4,5-d]pyrimidin-2-one
Inchi Key	AWOSLARSDHOWLE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H28N4O3S/c1-13-11-14(2)17(15(3)12-13)25-20-18(29-21(25)26)19(22-16(4)23-20)24(7-9-27-5)8-10-28-6/h11-12H,7-10H2,1-6H3
PubChem CID	9931738
ChEMBL	CHEMBL17656
IUPHAR	N/A
BindingDB	50076902
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
16227	Corticotropin-releasing factor receptor 1	P34998	CRHR1	Homo sapiens (Human)	444

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