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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3943580
Molecular formula	C30H25N5O2
IUPAC name	(3S)-2-oxo-N-(6-phenyl-5,6,7,8-tetrahydroquinolin-8-yl)spiro[1H-pyrrolo[2,3-b]pyridine-3,6'-5,7-dihydrocyclopenta[b]pyridine]-3'-carboxamide
Molecular weight	487.563
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	2.8
Synonyms	SCHEMBL16616018 US9227973, 5 isomer A US9227973, 6 isomer A BDBM200561
Inchi Key	AWNPJVVXALCZPP-JNEGJYOXSA-N
Inchi ID	InChI=1S/C30H25N5O2/c36-28(34-24-14-20(18-6-2-1-3-7-18)12-19-8-4-10-31-26(19)24)22-13-21-15-30(16-25(21)33-17-22)23-9-5-11-32-27(23)35-29(30)37/h1-11,13,17,20,24H,12,14-16H2,(H,34,36)(H,32,35,37)/t20?,24?,30-/m0/s1
PubChem CID	72194611
ChEMBL	CHEMBL3943580
IUPHAR	N/A
BindingDB	200561
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
536396	Calcitonin gene-related peptide type 1 receptor	Q16602	CALCRL	Homo sapiens (Human)	461

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