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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL427527
Molecular formula	C27H26F8N4
IUPAC name	N-(cyclopropylmethyl)-2,2,3,3,3-pentafluoro-N-[[2-(trifluoromethyl)-4-(2,4,6-trimethylphenyl)imidazo[1,2-a]benzimidazol-1-yl]methyl]propan-1-amine
Molecular weight	558.52
Hydrogen bond acceptor	10
Hydrogen bond donor	0
XlogP	8.4
Synonyms	BDBM50169523 Cyclopropylmethyl-(2,2,3,3,3-pentafluoro-propyl)-[2-trifluoromethyl-9-(2,4,6-trimethyl-phenyl)-9H-benzo[d]imidazo[1,2-a]imidazol-3-ylmethyl]-amine SCHEMBL14446543
Inchi Key	AUMRIJMIWHTOMW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H26F8N4/c1-15-10-16(2)22(17(3)11-15)39-20-7-5-4-6-19(20)38-21(23(26(30,31)32)36-24(38)39)13-37(12-18-8-9-18)14-25(28,29)27(33,34)35/h4-7,10-11,18H,8-9,12-14H2,1-3H3
PubChem CID	20780065
ChEMBL	CHEMBL427527
IUPHAR	N/A
BindingDB	50169523
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
14785	Corticotropin-releasing factor receptor 1	P34998	CRHR1	Homo sapiens (Human)	444

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