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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	BDBM228192
Molecular formula	C23H26F3N7O2S
IUPAC name	1-[2-[3-(2-cyclopropylpyrimidin-5-yl)-5-(trifluoromethyl)thiophen-2-yl]-6-methylpiperazin-1-yl]-2-[3-(methoxymethyl)-1,2,4-triazol-1-yl]ethanone
Molecular weight	521.563
Hydrogen bond acceptor	11
Hydrogen bond donor	1
XlogP	1.7
Synonyms	1-{(R)-4-[4-(2-Cyclopropyl-pyrimidin-5-yl)-2-trifluoromethyl-thiazol-5-yl]-2-methyl-piperazin-1-yl}-2-(3-methoxymethyl-[1,2,4]triazol-1-yl)-ethanone US10047080, 18
Inchi Key	ASICIYZNDVQTCS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H26F3N7O2S/c1-13-6-27-9-17(33(13)20(34)10-32-12-30-19(31-32)11-35-2)21-16(5-18(36-21)23(24,25)26)15-7-28-22(29-8-15)14-3-4-14/h5,7-8,12-14,17,27H,3-4,6,9-11H2,1-2H3
PubChem CID	134819795
ChEMBL	N/A
IUPHAR	N/A
BindingDB	228192
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
557652	C-X-C chemokine receptor type 3	P49682	CXCR3	Homo sapiens (Human)	368

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