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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL395748
Molecular formula	C32H25F3N4O4
IUPAC name	4-[4-oxo-2-[(1R)-1-[pyridin-3-ylmethyl-[2-[4-(trifluoromethyl)phenyl]acetyl]amino]ethyl]quinazolin-3-yl]benzoic acid
Molecular weight	586.571
Hydrogen bond acceptor	9
Hydrogen bond donor	1
XlogP	4.8
Synonyms	BDBM50211154 (R)-4-(4-oxo-2-(1-(N-(pyridin-3-ylmethyl)-2-(4-(trifluoromethyl)phenyl)acetamido)ethyl)quinazolin-3(4H)-yl)benzoic acid
Inchi Key	ARTJQOYGMHOOML-HXUWFJFHSA-N
Inchi ID	InChI=1S/C32H25F3N4O4/c1-20(29-37-27-7-3-2-6-26(27)30(41)39(29)25-14-10-23(11-15-25)31(42)43)38(19-22-5-4-16-36-18-22)28(40)17-21-8-12-24(13-9-21)32(33,34)35/h2-16,18,20H,17,19H2,1H3,(H,42,43)/t20-/m1/s1
PubChem CID	44426716
ChEMBL	CHEMBL395748
IUPHAR	N/A
BindingDB	50211154
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
12747	C-X-C chemokine receptor type 3	P49682	CXCR3	Homo sapiens (Human)	368

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