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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	GSK2210875
Molecular formula	C14H14N4O2S
IUPAC name	[(1R)-1-(6-methyl-[1,3]thiazolo[3,2-b][1,2,4]triazol-5-yl)ethyl] N-phenylcarbamate
Molecular weight	302.352
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	2.8
Synonyms	GSK-1222392 SCHEMBL4020104 GSK-329771 [(1R)-1-(6-methyl-[1,3]thiazolo[3,2-b][1,2,4]triazol-5-yl)ethyl] N-phenylcarbamate CHEMBL1630057 GSK-1635157 ZINC1404966 GSK-355089 AC1LSLDM GTPL6435 D0LP7W GSK-2210875 [(1R)-1-(6-methyl-[1,3]thiazolo[2,3-e][1,2,4]triazol-5-yl)ethyl] N-phenylcarbamate GSK-817755 [ Show all ]
Inchi Key	AOUUMBPBMVOBSP-SNVBAGLBSA-N
Inchi ID	InChI=1S/C14H14N4O2S/c1-9-12(21-13-15-8-16-18(9)13)10(2)20-14(19)17-11-6-4-3-5-7-11/h3-8,10H,1-2H3,(H,17,19)/t10-/m1/s1
PubChem CID	1489963
ChEMBL	CHEMBL1630057
IUPHAR	6435
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
10611	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212
10612	Metabotropic glutamate receptor 5	Q3UVX5	Grm5	Mus musculus (Mouse)	1203

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