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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SCHEMBL17254991
Molecular formula	C34H35F7N2O4
IUPAC name	2-[4-[5-[[2-[3,5-bis(trifluoromethyl)phenyl]-2-methylpropanoyl]-methylamino]-4-(4-fluoro-2-methylphenyl)-6-(hydroxymethyl)pyridin-2-yl]cyclohexyl]acetic acid
Molecular weight	668.653
Hydrogen bond acceptor	12
Hydrogen bond donor	2
XlogP	7.2
Synonyms	US9708266, 19 BDBM261495
Inchi Key	AOCBCZSDWBMPHN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C34H35F7N2O4/c1-18-11-24(35)9-10-25(18)26-16-27(20-7-5-19(6-8-20)12-29(45)46)42-28(17-44)30(26)43(4)31(47)32(2,3)21-13-22(33(36,37)38)15-23(14-21)34(39,40)41/h9-11,13-16,19-20,44H,5-8,12,17H2,1-4H3,(H,45,46)
PubChem CID	118509841
ChEMBL	N/A
IUPHAR	N/A
BindingDB	261495
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
557571	Substance-P receptor	P25103	TACR1	Homo sapiens (Human)	407

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