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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL380510
Molecular formula	C30H32F6N4O
IUPAC name	2-[3,5-bis(trifluoromethyl)phenyl]-N,2-dimethyl-N-[3-(2-methylphenyl)-6-(4-methylpiperazin-1-yl)pyridin-2-yl]propanamide
Molecular weight	578.603
Hydrogen bond acceptor	10
Hydrogen bond donor	0
XlogP	7.1
Synonyms	BDBM50178582 2-(3,5-bis(trifluoromethyl)phenyl)-N,2-dimethyl-N-(6-(4-methylpiperazin-1-yl)-3-o-tolylpyridin-2-yl)propanamide
Inchi Key	ANPYOUVKUYVENR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C30H32F6N4O/c1-19-8-6-7-9-23(19)24-10-11-25(40-14-12-38(4)13-15-40)37-26(24)39(5)27(41)28(2,3)20-16-21(29(31,32)33)18-22(17-20)30(34,35)36/h6-11,16-18H,12-15H2,1-5H3
PubChem CID	44409023
ChEMBL	CHEMBL380510
IUPHAR	N/A
BindingDB	50178582
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
9776	Substance-P receptor	P25103	TACR1	Homo sapiens (Human)	407

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