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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL584538
Molecular formula	C24H25FN2O3
IUPAC name	4-[(4-fluorophenyl)methoxy]-1-[4-(2-pyrrolidin-1-ylethoxy)phenyl]pyridin-2-one
Molecular weight	408.473
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	3.7
Synonyms	ZINC13983163 AKOS024458118 4-(4-Fluoro-benzyloxy)-1-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-1H-pyridin-2-one SCHEMBL2892783 BDBM50301081 MolPort-035-765-724 4-(4-fluorobenzyloxy)-1-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)pyridin-2(1H)-one TC-MCH 7c 864756-35-4 NCGC00379114-01 4-[(4-Fluorophenyl)methoxy]-1-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-2(1H)-pyridinone [ Show all ]
Inchi Key	ANCFKYJMXNMYNZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H25FN2O3/c25-20-5-3-19(4-6-20)18-30-23-11-14-27(24(28)17-23)21-7-9-22(10-8-21)29-16-15-26-12-1-2-13-26/h3-11,14,17H,1-2,12-13,15-16,18H2
PubChem CID	11654412
ChEMBL	CHEMBL584538
IUPHAR	N/A
BindingDB	50301081
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
9437	Melanin-concentrating hormone receptor 1	Q99705	MCHR1	Homo sapiens (Human)	422

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