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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL317209
Molecular formula	C25H23F6N3O3S
IUPAC name	1'-[3,5-bis(trifluoromethyl)benzoyl]-2-methyl-5-(thiophen-2-ylmethyl)spiro[6,6a-dihydro-3aH-pyrrolo[3,4-c]pyrrole-4,4'-piperidine]-1,3-dione
Molecular weight	559.527
Hydrogen bond acceptor	11
Hydrogen bond donor	0
XlogP	3.5
Synonyms	BDBM50217089 1'-[3,5-Bis(trifluoromethyl)benzoyl]-3-(2-thenyl)-7-methyl-3,7-diazaspiro[bicyclo[3.3.0]octane-2,4'-piperidine]-6,8-dione
Inchi Key	AMSYJCKYQVDRSP-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H23F6N3O3S/c1-32-21(36)18-13-34(12-17-3-2-8-38-17)23(19(18)22(32)37)4-6-33(7-5-23)20(35)14-9-15(24(26,27)28)11-16(10-14)25(29,30)31/h2-3,8-11,18-19H,4-7,12-13H2,1H3
PubChem CID	44334489
ChEMBL	CHEMBL317209
IUPHAR	N/A
BindingDB	50217089
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
9226	Substance-P receptor	P25103	TACR1	Homo sapiens (Human)	407

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