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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL318264
Molecular formula	C14H17N7O4
IUPAC name	(2R,3R,4S,5R)-2-[6-amino-2-(1-methylpyrazol-4-yl)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
Molecular weight	347.335
Hydrogen bond acceptor	9
Hydrogen bond donor	4
XlogP	-1.1
Synonyms	(2R,3R,4S,5R)-2-[6-Amino-2-(1-methyl-1H-pyrazol-4-yl)-purin-9-yl]-5-hydroxymethyl-tetrahydro-furan-3,4-diol BDBM50119162 SCHEMBL272005 2-(1-Methyl-1H-pyrazole-4-yl)adenosine
Inchi Key	AMMBIFRFVRSMSP-AKAIJSEGSA-N
Inchi ID	InChI=1S/C14H17N7O4/c1-20-3-6(2-17-20)12-18-11(15)8-13(19-12)21(5-16-8)14-10(24)9(23)7(4-22)25-14/h2-3,5,7,9-10,14,22-24H,4H2,1H3,(H2,15,18,19)/t7-,9-,10-,14-/m1/s1
PubChem CID	21054078
ChEMBL	CHEMBL318264
IUPHAR	N/A
BindingDB	50119162
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
9037	Adenosine receptor A2a	P30543	Adora2a	Rattus norvegicus (Rat)	410
9038	Adenosine receptor A2a	P29274	ADORA2A	Homo sapiens (Human)	412

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