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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL385959
Molecular formula	C32H41F3N4O2
IUPAC name	N-methyl-N-[(3S)-1-[(3R)-3-[methyl-(4-methylcyclohexyl)amino]pyrrolidine-1-carbonyl]pyrrolidin-3-yl]-4-[4-(trifluoromethyl)phenyl]benzamide
Molecular weight	570.701
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	5.9
Synonyms	BDBM50190270 4''-trifluoromethyl-biphenyl-4-carboxylic acid methyl-((S)-1-{(R)-3-[methyl-(4-methyl-cyclohexyl)-amino]-pyrrolidine-1-carbonyl}-pyrrolidin-3-yl)-amide
Inchi Key	ALGLCHGXJVZFRW-BYOMPTMESA-N
Inchi ID	InChI=1S/C32H41F3N4O2/c1-22-4-14-27(15-5-22)36(2)28-16-18-38(20-28)31(41)39-19-17-29(21-39)37(3)30(40)25-8-6-23(7-9-25)24-10-12-26(13-11-24)32(33,34)35/h6-13,22,27-29H,4-5,14-21H2,1-3H3/t22?,27?,28-,29+/m1/s1
PubChem CID	44415440
ChEMBL	CHEMBL385959
IUPHAR	N/A
BindingDB	50190270
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
8252	Melanin-concentrating hormone receptor 1	Q99705	MCHR1	Homo sapiens (Human)	422

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