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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1086142
Molecular formula	C22H28ClF3N4
IUPAC name	N-[[2-chloro-6-(trifluoromethyl)-1-(2,4,6-trimethylphenyl)imidazo[1,2-a]imidazol-5-yl]methyl]-N-ethylbutan-1-amine
Molecular weight	440.939
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	7.0
Synonyms	SCHEMBL5403586 BDBM50319898 N-((2-chloro-1-mesityl-6-(trifluoromethyl)-1H-imidazo[1,2-a]imidazol-5-yl)methyl)-N-ethylbutan-1-amine
Inchi Key	ALENSGWGHGELMK-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H28ClF3N4/c1-6-8-9-28(7-2)12-17-20(22(24,25)26)27-21-29(17)13-18(23)30(21)19-15(4)10-14(3)11-16(19)5/h10-11,13H,6-9,12H2,1-5H3
PubChem CID	21916321
ChEMBL	CHEMBL1086142
IUPHAR	N/A
BindingDB	50319898
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
8173	Corticotropin-releasing factor receptor 1	P34998	CRHR1	Homo sapiens (Human)	444

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