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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL263171
Molecular formula	C23H24F4N6O2
IUPAC name	N-[(2R)-5-(diaminomethylideneamino)-1-oxo-1-[[4-(trifluoromethyl)phenyl]methylamino]pentan-2-yl]-5-fluoro-1H-indole-2-carboxamide
Molecular weight	492.479
Hydrogen bond acceptor	7
Hydrogen bond donor	5
XlogP	2.7
Synonyms	(R)-5-fluoro-N-(5-guanidino-1-oxo-1-(4-(trifluoromethyl)benzylamino)pentan-2-yl)-1H-indole-2-carboxamide BDBM50198543
Inchi Key	AKFNZWADMIAXFH-GOSISDBHSA-N
Inchi ID	InChI=1S/C23H24F4N6O2/c24-16-7-8-17-14(10-16)11-19(32-17)21(35)33-18(2-1-9-30-22(28)29)20(34)31-12-13-3-5-15(6-4-13)23(25,26)27/h3-8,10-11,18,32H,1-2,9,12H2,(H,31,34)(H,33,35)(H4,28,29,30)/t18-/m1/s1
PubChem CID	44417941
ChEMBL	CHEMBL263171
IUPHAR	N/A
BindingDB	50198543
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
7492	Melanin-concentrating hormone receptor 1	Q99705	MCHR1	Homo sapiens (Human)	422

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