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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL65822
Molecular formula	C20H21NO3
IUPAC name	(11E)-11-[3-(dimethylamino)propylidene]-6H-benzo[c][1]benzoxepine-2-carboxylic acid
Molecular weight	323.392
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	1.5
Synonyms	11-(3-Dimethylamino-propylidene)-6,11-dihydro-dibenzo[b,e]oxepine-2-carboxylic acid; compound with but-2-enedioic acid BDBM50002095 SCHEMBL5056536 CHEMBL1179239 6,11-Dihydro-11-[(E)-3-dimethylaminopropylidene]dibenz[b,e]oxepin-2-carboxylic acid
Inchi Key	AJJNWHOAPWYEEB-CAOOACKPSA-N
Inchi ID	InChI=1S/C20H21NO3/c1-21(2)11-5-8-17-16-7-4-3-6-15(16)13-24-19-10-9-14(20(22)23)12-18(17)19/h3-4,6-10,12H,5,11,13H2,1-2H3,(H,22,23)/b17-8+
PubChem CID	14127191
ChEMBL	N/A
IUPHAR	N/A
BindingDB	50002095
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
6973	Histamine H1 receptor	P31389	HRH1	Cavia porcellus (Guinea pig)	488

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