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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SCHEMBL4536426
Molecular formula	C25H26N2O3
IUPAC name	5-(2,6-dimethoxyphenyl)-3-methyl-1-[(6-phenylpyridin-2-yl)methyl]pyrrolidin-2-one
Molecular weight	402.494
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	4.0
Synonyms	BDBM202989 5-(2,6-dimethoxyphenyl)-3-methyl-1-((6-phenylpyridin-2-yl)methyl)pyrrolidin-2-one US9242970, 138 AJINUHRTDLBLGI-UHFFFAOYSA-N CHEMBL3895679
Inchi Key	AJINUHRTDLBLGI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H26N2O3/c1-17-15-21(24-22(29-2)13-8-14-23(24)30-3)27(25(17)28)16-19-11-7-12-20(26-19)18-9-5-4-6-10-18/h4-14,17,21H,15-16H2,1-3H3
PubChem CID	69082588
ChEMBL	CHEMBL3895679
IUPHAR	N/A
BindingDB	202989
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
536115	Orexin receptor type 1	O43613	HCRTR1	Homo sapiens (Human)	425
536114	Orexin receptor type 2	O43614	HCRTR2	Homo sapiens (Human)	444

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