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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL278072
Molecular formula	C30H24ClN5S
IUPAC name	7-(2-chlorophenyl)-13-methyl-4-[3-(1,2,3,4-tetrahydrocarbazol-9-yl)prop-1-ynyl]-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaene
Molecular weight	522.067
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	6.6
Synonyms	AJAUSFIERKQXFW-UHFFFAOYSA-N 4-(2-Chlorophenyl)-9-methyl-2-[3-[(1,2,3,4-tetrahydro-9H-carbazol)-9-yl]-1-propynyl]-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine BDBM50011605 4-(2-Chloro-phenyl)-9-methyl-2-[3-(1,2,3,4-tetrahydro-carbazol-9-yl)-prop-1-ynyl]-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulene SCHEMBL9378336 4-(2-chlorophenyl)-2-[3-(1,2,3,4-tetrahydro 9H-carbazol-9-yl)-1-propynyl]-9-methyl-6H-thieno-[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine [ Show all ]
Inchi Key	AJAUSFIERKQXFW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C30H24ClN5S/c1-19-33-34-28-18-32-29(23-12-2-5-13-25(23)31)24-17-20(37-30(24)36(19)28)9-8-16-35-26-14-6-3-10-21(26)22-11-4-7-15-27(22)35/h2-3,5-6,10,12-14,17H,4,7,11,15-16,18H2,1H3
PubChem CID	14851891
ChEMBL	CHEMBL278072
IUPHAR	N/A
BindingDB	50011605
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
6724	Platelet-activating factor receptor	P25105	PTAFR	Homo sapiens (Human)	342

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