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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL185136
Molecular formula	C19H20Cl2N2O3
IUPAC name	1-(2,4-dichlorophenyl)-3-[(4S,5S)-2,2-dimethyl-4-phenyl-1,3-dioxan-5-yl]urea
Molecular weight	395.28
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	4.0
Synonyms	1-(2,4-Dichloro-phenyl)-3-((4S,5S)-2,2-dimethyl-4-phenyl-[1,3]dioxan-5-yl)-urea BDBM50412862 SCHEMBL6352846 AILCJWWDSWGJPE-IRXDYDNUSA-N
Inchi Key	AILCJWWDSWGJPE-IRXDYDNUSA-N
Inchi ID	InChI=1S/C19H20Cl2N2O3/c1-19(2)25-11-16(17(26-19)12-6-4-3-5-7-12)23-18(24)22-15-9-8-13(20)10-14(15)21/h3-10,16-17H,11H2,1-2H3,(H2,22,23,24)/t16-,17-/m0/s1
PubChem CID	10453273
ChEMBL	CHEMBL185136
IUPHAR	N/A
BindingDB	50412862
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
6320	Orexin receptor type 1	O43613	HCRTR1	Homo sapiens (Human)	425
6319	Orexin receptor type 2	O43614	HCRTR2	Homo sapiens (Human)	444

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