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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL213491
Molecular formula	C31H32Cl2N4O
IUPAC name	2-[6-(3-cyanophenyl)-1'-propan-2-ylspiro[3,4-dihydroisoquinoline-1,4'-piperidine]-2-yl]-N-(3,5-dichlorophenyl)acetamide
Molecular weight	547.524
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	6.5
Synonyms	BDBM50190905 2-[6-(3-cyano-phenyl)-1''-isopropyl-3,4-dihydro-spiro[isoquinoline-1,4''-piperidin]-2-yl]-N-(3,5-dichloro-phenyl)-acetamide
Inchi Key	AIHWMRGISSLYBL-UHFFFAOYSA-N
Inchi ID	InChI=1S/C31H32Cl2N4O/c1-21(2)36-12-9-31(10-13-36)29-7-6-24(23-5-3-4-22(14-23)19-34)15-25(29)8-11-37(31)20-30(38)35-28-17-26(32)16-27(33)18-28/h3-7,14-18,21H,8-13,20H2,1-2H3,(H,35,38)
PubChem CID	10256914
ChEMBL	CHEMBL213491
IUPHAR	N/A
BindingDB	50190905
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
6228	Melanin-concentrating hormone receptor 1	Q99705	MCHR1	Homo sapiens (Human)	422

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