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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3741065
Molecular formula	C23H19ClN2O4
IUPAC name	1-[(2-chlorophenyl)methyl]-3-(3,4-dimethoxyphenyl)quinazoline-2,4-dione
Molecular weight	422.865
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	4.4
Synonyms	F0922-0211 ZINC9616094 899922-83-9 MCULE-8797161680 1-(2-chlorobenzyl)-3-(3,4-dimethoxyphenyl)quinazoline-2,4(1H,3H)-dione AKOS001789993 EU-0091094 MolPort-007-608-326 1-[(2-chlorophenyl)methyl]-3-(3,4-dimethoxyphenyl)-1,2,3,4-tetrahydroquinazoline-2,4-dione [ Show all ]
Inchi Key	AGVDSFYCZYCKNF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H19ClN2O4/c1-29-20-12-11-16(13-21(20)30-2)26-22(27)17-8-4-6-10-19(17)25(23(26)28)14-15-7-3-5-9-18(15)24/h3-13H,14H2,1-2H3
PubChem CID	16002587
ChEMBL	CHEMBL3741065
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
521614	Orexin receptor type 1	O43613	HCRTR1	Homo sapiens (Human)	425
521615	Orexin receptor type 2	O43614	HCRTR2	Homo sapiens (Human)	444

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