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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL303380
Molecular formula	C19H23Cl2N5
IUPAC name	N-butyl-3-(2,4-dichlorophenyl)-N-ethyl-2,5-dimethylpyrazolo[4,3-d]pyrimidin-7-amine
Molecular weight	392.328
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	5.3
Synonyms	N-Ethyl-N-butyl-2,5-dimethyl-3-(2,4-dichlorophenyl)-2H-pyrazolo[4,3-d]pyrimidine-7-amine BDBM50116123 Butyl-[3-(2,4-dichloro-phenyl)-2,5-dimethyl-2H-pyrazolo[4,3-d]pyrimidin-7-yl]-ethyl-amine
Inchi Key	AGQQWJNSMXZLLB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H23Cl2N5/c1-5-7-10-26(6-2)19-17-16(22-12(3)23-19)18(25(4)24-17)14-9-8-13(20)11-15(14)21/h8-9,11H,5-7,10H2,1-4H3
PubChem CID	44307491
ChEMBL	CHEMBL303380
IUPHAR	N/A
BindingDB	50116123
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
5127	Corticotropin-releasing factor receptor 1	P34998	CRHR1	Homo sapiens (Human)	444

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