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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000072923
Molecular formula	C24H24N6O3
IUPAC name	6-imino-11-methyl-2-oxo-N-(oxolan-2-ylmethyl)-7-(pyridin-3-ylmethyl)-1,7,9-triazatricyclo[8.4.0.03,8]tetradeca-3(8),4,9,11,13-pentaene-5-carboxamide
Molecular weight	444.495
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	0.7
Synonyms	2-azanylidene-10-methyl-5-oxidanylidene-N-(oxolan-2-ylmethyl)-1-(pyridin-3-ylmethyl)dipyrido[3,4-c:1'',2''-f]pyrimidine-3-carboxamide AC1LCLFX HMS2349A15 ST50090483 2-imino-10-methyl-5-oxo-N-(2-oxolanylmethyl)-1-(3-pyridinylmethyl)-3-dipyrido[3,4-c:1'',2''-f]pyrimidinecarboxamide BAS 04995535 MLS002534459 2-Imino-8-methyl-10-oxo-1-pyridin-3-ylmethyl-1,10-dihydro-2H-1,9,10a-triaza-anthracene-3-carboxylic acid (tetrahydro-furan-2-ylmethyl)-amide CHEMBL1578543 SCHEMBL13856695 2-imino-10-methyl-5-oxo-1-(3-pyridinylmethyl)-N-(tetrahydro-2-furanylmethyl)-1,5-dihydro-2H-dipyrido[1,2-a:2,3-d]pyrimidine-3-carboxamide AKOS000529001 MCULE-3325880967 STK703659 2-imino-10-methyl-5-oxo-N-(oxolan-2-ylmethyl)-1-(pyridin-3-ylmethyl)dipyrido[3,4-c:1'',2''-f]pyrimidine-3-carboxamide BDBM40574 MolPort-000-210-352 510761-55-4 cid_652081 SMR000013118 2-imino-10-methyl-5-oxo-1-(pyridin-3-ylmethyl)-N-(tetrahydrofuran-2-ylmethyl)-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide AKOS016069780 [2-imino-10-methyl-5-oxo-1-(3-pyridylmethyl)(1,6-dihydropyridino[2,3-d]pyridin o[1,2-a]pyrimidin-3-yl)]-N-(oxolan-2-ylmethyl)carboxamide 2-imino-5-keto-10-methyl-1-(3-pyridylmethyl)-N-(tetrahydrofurfuryl)dipyrido[3,4-c:1'',2''-f]pyrimidine-3-carboxamide Oprea1_062411 [ Show all ]
Inchi Key	AFJDCYRFFYKKSA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H24N6O3/c1-15-5-3-9-29-21(15)28-22-19(24(29)32)11-18(23(31)27-13-17-7-4-10-33-17)20(25)30(22)14-16-6-2-8-26-12-16/h2-3,5-6,8-9,11-12,17,25H,4,7,10,13-14H2,1H3,(H,27,31)
PubChem CID	652081
ChEMBL	CHEMBL1578543
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
4202	Relaxin receptor 1	Q9HBX9	RXFP1	Homo sapiens (Human)	757

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