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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SCHEMBL16463160
Molecular formula	C23H18F4N6O3
IUPAC name	[2-fluoro-3-methyl-6-(triazol-2-yl)phenyl]-[(2S)-2-[3-[2-(trifluoromethoxy)phenyl]-1,2,4-oxadiazol-5-yl]pyrrolidin-1-yl]methanone
Molecular weight	502.43
Hydrogen bond acceptor	11
Hydrogen bond donor	0
XlogP	4.9
Synonyms	US9493446, 145 BDBM257675
Inchi Key	AEVKXGFMSDEVKH-INIZCTEOSA-N
Inchi ID	InChI=1S/C23H18F4N6O3/c1-13-8-9-15(33-28-10-11-29-33)18(19(13)24)22(34)32-12-4-6-16(32)21-30-20(31-36-21)14-5-2-3-7-17(14)35-23(25,26)27/h2-3,5,7-11,16H,4,6,12H2,1H3/t16-/m0/s1
PubChem CID	73775853
ChEMBL	N/A
IUPHAR	N/A
BindingDB	257675
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
536019	Orexin receptor type 1	O43613	HCRTR1	Homo sapiens (Human)	425
536018	Orexin receptor type 2	O43614	HCRTR2	Homo sapiens (Human)	444

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