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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3742398
Molecular formula	C23H20F2N2O6S
IUPAC name	4-[(2,6-difluoro-4-methoxyphenyl)methyl]-2-(3,4-dimethoxyphenyl)-1,1-dioxo-1lambda6,2,4-benzothiadiazin-3-one
Molecular weight	490.478
Hydrogen bond acceptor	8
Hydrogen bond donor	0
XlogP	3.7
Synonyms	SCHEMBL15557193 2-(3,4-Dimethoxyphenyl)-4-(2,6-difluoro-4-methoxybenzyl)-2H-1,2,4-benzothiadiazin-3(4H)-one 1,1-dioxide AESOLJVLORXMKZ-UHFFFAOYSA-N
Inchi Key	AESOLJVLORXMKZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H20F2N2O6S/c1-31-15-11-17(24)16(18(25)12-15)13-26-19-6-4-5-7-22(19)34(29,30)27(23(26)28)14-8-9-20(32-2)21(10-14)33-3/h4-12H,13H2,1-3H3
PubChem CID	72721987
ChEMBL	CHEMBL3742398
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
521552	Orexin receptor type 1	O43613	HCRTR1	Homo sapiens (Human)	425
521551	Orexin receptor type 2	O43614	HCRTR2	Homo sapiens (Human)	444

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