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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SMR000006848
Molecular formula	C18H20N4O
IUPAC name	N-[2-[(3-cyano-7,8-dimethylquinolin-2-yl)amino]ethyl]cyclopropanecarboxamide
Molecular weight	308.385
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	3.3
Synonyms	N-[2-[(3-cyano-7,8-dimethylquinolin-2-yl)amino]ethyl]cyclopropanecarboxamide CHEMBL1328534 HMS2400G19 SR-01000329169-1 AC1LDI3K N-[2-[(3-cyano-7,8-dimethyl-2-quinolyl)amino]ethyl]cyclopropanecarboxamide BDBM74551 cid_648434 MLS000033154 ZINC20151399 AKOS000680518 N-[2-[(3-cyano-7,8-dimethyl-quinolin-2-yl)amino]ethyl]cyclopropanecarboxamide Cyclopropanecarboxylic acid [2-(3-cyano-7,8-dimethyl-quinolin-2-ylamino)-ethyl]-amide SR-01000329169 N-[2-[(3-cyano-7,8-dimethyl-2-quinolinyl)amino]ethyl]cyclopropanecarboxamide ASN 06539975 [ Show all ]
Inchi Key	ADYKIWQYRJDHRU-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H20N4O/c1-11-3-4-14-9-15(10-19)17(22-16(14)12(11)2)20-7-8-21-18(23)13-5-6-13/h3-4,9,13H,5-8H2,1-2H3,(H,20,22)(H,21,23)
PubChem CID	648434
ChEMBL	CHEMBL1328534
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
3223	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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