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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL309992
Molecular formula	C22H26N4O4
IUPAC name	8-[3-(4-nitrophenoxy)propyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
Molecular weight	410.474
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	3.1
Synonyms	8-[3-(4-Nitro-phenoxy)-propyl]-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one 8-[3-(4-nitrophenoxy)propyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one BDBM50044456
Inchi Key	ADEWDPHDHCJVIC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H26N4O4/c27-21-22(25(17-23-21)18-5-2-1-3-6-18)11-14-24(15-12-22)13-4-16-30-20-9-7-19(8-10-20)26(28)29/h1-3,5-10H,4,11-17H2,(H,23,27)
PubChem CID	14968322
ChEMBL	CHEMBL309992
IUPHAR	N/A
BindingDB	50044456
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
2194	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
2193	5-hydroxytryptamine receptor 2C	P08909	Htr2c	Rattus norvegicus (Rat)	460

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