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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL224114
Molecular formula	C26H20Cl3N3O
IUPAC name	12-chloro-3-(2,4-dichlorophenyl)-N-(4-methylphenyl)-3,4-diazatricyclo[8.4.0.02,6]tetradeca-1(10),2(6),4,11,13-pentaene-5-carboxamide
Molecular weight	496.816
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	7.8
Synonyms	8-chloro-1-(2'',4''-dichlorophenyl)-N-p-methylphenyl-1,4,5,6-tetrahydrobenzo[6,7]cyclohepta[1,2-c]pyrazole-3-carboxamide BDBM50176991
Inchi Key	ADAPNBZDCCCWBS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H20Cl3N3O/c1-15-5-9-19(10-6-15)30-26(33)24-21-4-2-3-16-13-17(27)7-11-20(16)25(21)32(31-24)23-12-8-18(28)14-22(23)29/h5-14H,2-4H2,1H3,(H,30,33)
PubChem CID	11533349
ChEMBL	CHEMBL224114
IUPHAR	N/A
BindingDB	50176991
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
2084	Cannabinoid receptor 1	P47746	Cnr1	Mus musculus (Mouse)	473
2085	Cannabinoid receptor 2	P47936	Cnr2	Mus musculus (Mouse)	347

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