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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SCHEMBL1671105
Molecular formula	C27H23FN4O
IUPAC name	[2-(4-fluorophenyl)phenyl]-(2-quinoxalin-2-yl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl)methanone
Molecular weight	438.506
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	4.6
Synonyms	CHEMBL3646179 BDBM118375 2-{5-[(4'-Fluorobiphenyl-2-yl)carbonyl]hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}quinoxaline US8653263, 28 ACYFNSJZZLHDLT-UHFFFAOYSA-N
Inchi Key	ACYFNSJZZLHDLT-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H23FN4O/c28-21-11-9-18(10-12-21)22-5-1-2-6-23(22)27(33)32-16-19-14-31(15-20(19)17-32)26-13-29-24-7-3-4-8-25(24)30-26/h1-13,19-20H,14-17H2
PubChem CID	52916933
ChEMBL	CHEMBL3646179
IUPHAR	N/A
BindingDB	118375
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
2027	Orexin receptor type 1	O43613	HCRTR1	Homo sapiens (Human)	425
2026	Orexin receptor type 2	O43614	HCRTR2	Homo sapiens (Human)	444

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