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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
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Ligand

Name	137862-87-4
Molecular formula	C24H29N5O3
IUPAC name	(2R)-3-methyl-2-[pentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoic acid
Molecular weight	435.528
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	4.4
Synonyms	(2R)-3-methyl-2-[pentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoic acid ANW-49605 CHEMBL115622 ent-Valsartan S-7514 Valsartan related compound A [USP] (R)-2-(N-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)pentanamido)-3-methylbutanoic acid AB0068858 BDBM50282371 D-Valsartan J-007070 Tox21_111447 Valsartan, D- (2R)-3-Methyl-2-(pentanoyl((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)amino)butanoic acid (R)-3-Methyl-2-{pentanoyl-[2''-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-amino}-butyric acid AKOS015854410 CGP-49309 DSSTox_RID_77173 N-VALERYL-N-{[2'-(1HTETRAZOLE-5-YL)-BIPHENYL-4-YL]-METHYL}-D-VALINE(ent-Valsartan)(Valsartan Related Compound A), Pharmaceutical Secondary Standard; Certified Reference Material Valsartan related compound A (2R)-3-methyl-2-[pentanoyl-[[4-[2-(1H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoic acid (2R)-3-Methyl-2-[pentanoyl[[2'(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]amino]butanoic Acid API0012846 CTK8B5685 FT-0675772 SCHEMBL2328 Valsartan Related Compound A, United States Pharmacopeia (USP) Reference Standard (r)-2-(n-((2-(1h-tetrazol-5-yl)-[1,1-biphenyl]-4-yl)methyl)pentanamido)-3-methylbutanoic acid AC1NR4SZ BR-39369 DSSTox_CID_3735 N-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-N-pentanoyl-D-valine TR-005022 ZINC3831602 (2R)-3-methyl-2-[1-oxopentyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoic acid (R)-N-Valeryl-N-([2'-(1H-tetrazole-5-yl)-biphenyl-4-yl]-Methyl)-valine AKOS026751459 DTXSID6023735 NCGC00095139-01 Valsartan related compound A RS [USP] (2R)-3-methyl-2-[pentanoyl-[[4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoic acid (2R)-3-Methyl-2-[pentanoyl[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]amino]butanoic Acid (Valsartan (R)-Enantiomer) A807313 AX8164352 D-Valine, N-(1-oxopentyl)-N-((2'-(2H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)- IDC67444MI ST24026402 Valsartan specified impurity A [EP] (R)-2-(N-((2;-(1H-Tetrazol-5-yl)-[1,1;-biphenyl]-4-yl)methyl)pentanamido)-3-methylbutanoic acid AK-39369 CAS-137862-53-4 DSSTox_GSID_23735 N-pentanoyl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-D-valine UNII-IDC67444MI [(R-N-valeryl-N-([2'-(1H-tetrazole-5-yl)biphen-4-yl]methyl)valine) (2R)-3-methyl-2-[N-({4-[2-(1H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)pentanamido]butanoic acid [ Show all ]
Inchi Key	ACWBQPMHZXGDFX-JOCHJYFZSA-N
Inchi ID	InChI=1S/C24H29N5O3/c1-4-5-10-21(30)29(22(16(2)3)24(31)32)15-17-11-13-18(14-12-17)19-8-6-7-9-20(19)23-25-27-28-26-23/h6-9,11-14,16,22H,4-5,10,15H2,1-3H3,(H,31,32)(H,25,26,27,28)/t22-/m1/s1
PubChem CID	5284633
ChEMBL	CHEMBL115622
IUPHAR	N/A
BindingDB	50282371
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
1985	Type-1 angiotensin II receptor	P30556	AGTR1	Homo sapiens (Human)	359

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